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Sixty elderly men were put on various Ostarine dosages for 3 months, and it was found that simply taking 3mg of Ostarine per day led to an increase in muscle mass by 1.5 points over baseline. Although the magnitude of this effect was not statistically significant, taking this medication daily for 3 months could help improve muscle strength in those individuals who have been shown to have a low testosterone level. 3.2 How is Ostarine Supplied? Ostarin is a dihydro-α-hydroxy androgenase (DHEA) inhibitor. To obtain its potency, Ostarin is synthesized in large amounts from DHEA and has a long half-life. In a drug discovery process that was published in 2005, an additional two methyl groups and carbon dioxide were added to the DHEA-derived dihydro O-α-hydroxy-DHEA-3-glycerophenone (O-α-hydroxy-DHEA-3-glycerophenone) to increase the amount of active metabolite which can then be excreted in the urine. At the time of this publication, we conducted a Phase 2a clinical trial of ostarine to assess whether it would be effective for the treatment of muscle weakness in subjects with impaired muscle strength. The aim of this trial was to determine whether a reduction in body mass index (BMI) after 3 months of treatment with Ostarine will improve muscle strength, a commonly reported outcome of muscle weakness in men and women. We enrolled 22 healthy, otherwise healthy men with normal or slightly increased BMI and a lower percentage of muscle strength for both men and women, at the University of Melbourne Hospital from February 28, 2008, to August 30, 2008. The men were randomized to receive Ostarine or placebo at a rate of 2 mg per day for 3 months with a target dose of 10 mg per day for the 6 months after that. The study was completed in July, 2009, and the trial ended on December 31, 2009. At month 3, we measured the subjects' BMD using dual-energy X-ray absorptiometry (DXA). The DXA data revealed that the subjects with lower body strength had significantly lower DXA levels than the men who had normal strength. This was not an insignificant difference for men with normal and below-normal strength for both men and women. There were no significant differences in body weight, height, or percentage of body weight at month 3 for the subjects with normal and below-normal strength. 3.3 What were the main findings? We found that both placebo and ostarine were effective Similar articles: